𝔖 Bobbio Scriptorium
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OCTN genes: Susceptibility genes for autoimmune diseases?

✍ Scribed by E. Urcelay; E.G. de la Concha; A. Martínez

Book ID
117419445
Publisher
Grupo Aran
Year
2007
Tongue
Spanish
Weight
109 KB
Volume
26
Category
Article
ISSN
0213-9626

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The gene responsible for the lpr mutation in MRL mice that are prone to systemic lupus erythematosus has been shown to encode the apoptosis-inducing Fas antigen, thus pointing to control of apoptosis as a major regulatory mechanism in autoimmunity. In the non-obese diabetic mouse model for insulin-d