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Octanoic Acid Suppresses Harmaline-Induced Tremor in Mouse Model of Essential Tremor

✍ Scribed by Nahab, Fatta B.; Handforth, Adrian; Brown, Tyler; Shin, Christopher; Quesada, Arnulfo; Dong, Chuanhui; Haubenberger, Dietrich; Hallett, Mark


Book ID
118303044
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
104 KB
Volume
9
Category
Article
ISSN
1933-7213

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## Abstract Excessive olivo‐cerebellar synchrony is implicated in essential tremor. Because synchrony in some networks is mediated by gap junctions, we examined whether the gap junction blockers heptanol, octanol, carbenoxolone, and mefloquine suppress tremor in the mouse harmaline model, and perfo