We investigated the distribution of messenger RNAs coding for flip and flop splice variants ofAMPA receptor subunits in the human cerebellum to determine the relevance of AMPA receptors in the selective vulnerability of Purkinje cells to ischemia. Purkinje cells more abundantly expressed transcripts
Occurrence of fluorescent granules in the Purkinje cells of the cerebellum
β Scribed by Sarnat, Harvey B.
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- English
- Weight
- 469 KB
- Volume
- 162
- Category
- Article
- ISSN
- 0003-276X
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β¦ Synopsis
When examined in the fluorescence microscope, cells of the central nervous system exhibit intense, yellow, naturally fluorescent granules throughout their cytoplasm. In the mouse, cat and man, the granules are absent at birth and present in adults. A study of the development of these granules in the Purkinje cells of the cerebellum was made in the mouse and cat. There is a rapid increase in the number of fluorescent granules in postnatal life. The granules probably represent lysosomes.
Methods
1 SUDDOrkd in Dart bv U.
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