𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Occurrence of fetoprotein in patients with neoplasms and non-neoplastic diseases

✍ Scribed by J. Masopust; K. Kithier; J. Rádl; J. Koutecký; L. Kotál

Publisher
John Wiley and Sons
Year
1968
Tongue
French
Weight
760 KB
Volume
3
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Sera from 248 pafieuts, children and adu/ts with various tumors, and j i o m 484 patients with diffcwnt non-tumorous diseases, were examined for the presence of fhtoprotein by immunochemical methods and specijic anti-jetal protein antiserum absorbed with serum of adult individuals. The results show that fktoprotein appears in two types of tumors only: I ) in hepatocellular carcinoma, and 2 ) in malignant undijjierentiated teratoma. In other types of neoplasms including embryonal tumors composed of more or less differentiated tissue, as well as in cases of nephroblastotna, sympathicoblastoma, chorionepitkelioma and dysgerminoma, fetoprotein was not detected in any patient.

Fetoprotein can occur in the .first year of lif. in some patients suffering from hepatitis or some other liver disease. However, its concentration is low and it has a tendency to disappear with the regression of the disease. Fetoprotein was not detected, however, in patients sufering from non-malignant diseases, including hepatitis, after the .first year of life.

📜 SIMILAR VOLUMES

I131 albumin degradation in patients wit
I131 albumin degradation in patients with neoplastic diseases
✍ Jesse L. Steinfeld 📂 Article 📅 1960 🏛 John Wiley and Sons 🌐 English ⚖ 832 KB

UBNORMAL serum albumin and total pro-S tein concentrations had been reported in patients suffering from a variety of neoplastic diseases as early as 1928.179 30, 3 7 ~3 9 However, the quantitative significance of this finding was unknown in view of the fact that many of the salting-out techniqueP us

Detection of hepatic oxidative DNA damag
Detection of hepatic oxidative DNA damage in patients with hepatoblastoma and children with non-neoplastic disease
✍ Ikeda, Hitoshi ;Hirato, Junko ;Suzuki, Norio ;Kuroiwa, Minoru ;Maruyama, Kenichi 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 265 KB

## Abstract ## Background The authors have revealed a significant association between hepatoblastoma and low birth weight. This study was done to explore the evidence that liver cells were oxidatively damaged, based on the hypothesis that oxidative damage to DNA is involved in the development of h