I131 albumin degradation in patients with neoplastic diseases

✍ Scribed by Jesse L. Steinfeld

• Publisher: John Wiley and Sons
• Year: 1960
• Tongue: English
• Weight: 832 KB
• Volume: 13
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(196009/10)13:5<974::aid-cncr2820130519>3.0.co;2-y

✦ Synopsis

UBNORMAL serum albumin and total pro-S tein concentrations had been reported in patients suffering from a variety of neoplastic diseases as early as 1928.179 30, 3 7 ~3 9 However, the quantitative significance of this finding was unknown in view of the fact that many of the salting-out techniqueP used for determination of serum albumin measured not only albumin but varying proportions of alpha and beta globul.in.24, 31, 34, 35 T h e concentrations of serum alpha and beta globulins simi-TABLE 1 TRATION WITH EXTENT OF CANCER* VARIATION IN SERUM ALBUMIN CONCEN-Extent ca. No. Albumin, Pt. gm./100 cc. Superficial localized 40 3 . 3 7 f 0 . 0 4 Internal localized 50 3.1SfO .07 Superficial advanced 26 2.84f0 ,09 Internal advanced 71 2 . 8 2 f 0 . 0 6 Late 35 2 . 3 8 f 0 . 0 5 All ca. 222 2 . 9 4 f 0 . 0 4 Normal adults . . . 4.04f0.