Occludin dislocation in brain capillary endothelium of rats with bile duct ligation induced cholestasis
β Scribed by Adamantios G. Mavrakis; Sophia Havaki; Evangelos Marinos; Elisabeth Chroni; Dimitris Konstantinou
- Book ID
- 118488127
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 728 KB
- Volume
- 528
- Category
- Article
- ISSN
- 0304-3940
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During bile duct ligation (BDL), the growth of large cholangiocytes is regulated by the cyclic adenosine monophosphate (cAMP)/extracellular signal-regulated kinase 1/2 (ERK1/2) pathway and is closely associated with increased secretin receptor (SR) expression. Although it has been suggested that SR
Studies of the pathogenesis of hepatic encephalopathy are hampered by the lack of a satisfactory animal model. We examined the neurological features of rats after bile duct ligation fed a hyperammonemic diet (BDL+HD). Six groups were studied: sham, sham pair-fed, hyperammonemic, bile duct ligation (