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OC1.08.1 THE ATYPICAL CHEMOKINE RECEPTOR D6 CONTROLS INTESTINAL INFLAMMATION AND INFLAMMATION-ASSOCIATED COLON CANCER

✍ Scribed by S. Vetrano; C. Correale; E. Borroni; R. Bonecchi; V. Arena; M. Fantini; A. Malesci; A. Vecchi; A. Mantovani; M. Locati; S. Danese


Book ID
119632543
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
80 KB
Volume
40
Category
Article
ISSN
1590-8658

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Background: Vanin-1 is an epithelial pantetheinase that provides cysteamine to tissue and regulates response to stress. Vanin-1 is expressed by enterocytes, and its absence limits intestinal epithelial cell production of proinflammatory signals. A link between chronic active inflammation and cancer