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401 The Atypical Chemokine Receptor D6 Controls Intestinal Inflammation and Inflammation-Associated Colon Cancer

✍ Scribed by Stefania Vetrano; Elena Borroni; Raffaella Bonecchi; Carmen Correale; Vincenzo Arena; Massimo C. Fantini; Alberto Malesci; Annunciata Vecchi; Alberto Mantovani; Massimo Locati; Silvio Danese

Book ID
119428139
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
98 KB
Volume
134
Category
Article
ISSN
0016-5085

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Background: Vanin-1 is an epithelial pantetheinase that provides cysteamine to tissue and regulates response to stress. Vanin-1 is expressed by enterocytes, and its absence limits intestinal epithelial cell production of proinflammatory signals. A link between chronic active inflammation and cancer