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OC-04 The role of platelet microparticles in angiogenesis and tumor biology

✍ Scribed by A. Brill; O. Dashevsky; T. Zelikovitz; D. Varon

Book ID
117257831
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
48 KB
Volume
120
Category
Article
ISSN
0049-3848

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Thrombospondin (TSP-1) is a large glycoprotein secreted by platelets and synthesized by many cell types, including endothelial and tumor cells. Although controversy exists about the biological function of TSP-1, the following observations suggest that TSP-1 may potentiate tumor progression. (1) Tumo