๐”– Bobbio Scriptorium
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Observations on the site of 6-chloropurine-induced inhibition of purine biosynthesis

โœ Scribed by Alan C. Sartorelli; Barbara A. Booth


Book ID
115791406
Publisher
Elsevier Science
Year
1962
Weight
158 KB
Volume
55
Category
Article
ISSN
0006-3002

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The effect of inhibiting endogenous brain thromboxane (TXB2) on pentylenetetrazole-induced seizures was studied using the thromboxane synthetase inhibitors OKY-1581 (20 mgikg) and UK 38,485 (50 mgikg). Both compounds selectively decreased ( > 90%) TXB2 production in brain measured after 2 min of con