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Observations on the micelle formation of 2-butyl-3-benzofuranyl 4-[ 2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride (SK&F 33 134-A) by NMR spectroscopy

โœ Scribed by Richard J. Warren; R. John Stedman; Elie G. Shami; Elisabeth S. Rattie; Louis J. Ravin


Publisher
John Wiley and Sons
Year
1970
Tongue
English
Weight
166 KB
Volume
59
Category
Article
ISSN
0022-3549

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Effect of polysorbate 80 on the solubili
โœ Louis J. Ravin; Elie G. Shami; Alfred Intoccia; Elisabeth Rattie; Gerald Joseph ๐Ÿ“‚ Article ๐Ÿ“… 1969 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 425 KB

Polysorbate 80 has been shown to have a significant effect on the solubility of 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride (SK&F 33134-A). Subsequent in uiuo studies in bile-cannulated rats with SK&F 33134-A-14C indicated that the drug was better absorbed