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Micelle formation and its relationship to solubility behavior of 2-butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride

โœ Scribed by Louis J. Ravin; Elie G. Shami; Elisabeth S. Rattie


Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
371 KB
Volume
64
Category
Article
ISSN
0022-3549

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Effect of polysorbate 80 on the solubili
โœ Louis J. Ravin; Elie G. Shami; Alfred Intoccia; Elisabeth Rattie; Gerald Joseph ๐Ÿ“‚ Article ๐Ÿ“… 1969 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 425 KB

Polysorbate 80 has been shown to have a significant effect on the solubility of 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride (SK&F 33134-A). Subsequent in uiuo studies in bile-cannulated rats with SK&F 33134-A-14C indicated that the drug was better absorbed