Observation of precrystallization aggregation in protein solutions during centrifugation
β Scribed by Joachim Behlke; Andreas Knespel
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 262 KB
- Volume
- 158
- Category
- Article
- ISSN
- 0022-0248
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π SIMILAR VOLUMES
Solution conditions greatly affect the aggregation rate of a protein. Elucidating these influences provides insight into the critical factors governing aggregation. In this study, recombinant human botulinum protein antigen serotype C [rBoNTC (H(c))] was employed as a model protein. rBoNTC (H(c)) ag
**The cover picture shows** a surface plot representation of the trajectories of a single quantum dot (larger signals in the back) and of a single fluorescent antibody (four smaller signals in the front) in aqueous buffer solution. In their Communication on page 812 GrΓΌnwald et al. show that imaging