Observation of mixed molecular cluster ions in matrix-assisted UV laser desorption/ionization of high mass protein mixtures
โ Scribed by I.K. Perera; D. Allwood; P.E. Dyer; G.A. Oldershaw
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 489 KB
- Volume
- 145
- Category
- Article
- ISSN
- 0168-1176
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
While electrospray (ESI) mass spectrometry has already established its potential for the characterization of noncovalent protein complexes, matrix-assisted laser desorption/ionization mass spectrometry (MALDI/MS) seemed not to be applicable hitherto because of limitations in matrix chemistry and sam
## Abstract We have developed a simple and effective means of using alkylammonium ionโpairing agents, such as cetyltetramethylammonium bromide, to recover matrix assisted laser desorption/ionization mass spectrometric (MALDIโMS) signals from sodium dodecyl sulfate (SDS)โcontaining protein and pepti
Transition metal ion complexes with proteins and peptides are important in many areas of analytical and biological chemistry. We used positive and negative ion MALDI-MS to detect complexes with Cu and Ni ions, and show that the speciรc and non-speciรc transition metal ion-peptide complexes can be di
The mechanisms of ion formation in matrix-assisted laser desorption/ionization mass spectrometry are still largely unknown. Ions may exist as pre-formed species in the solid state, or may form by ion-molecule reactions initiated by the laser shot, or, most probably, they may originate from a combina