O83. Validation of an expression profile for prediction of lymph node metastasis from primary head and neck squamous cell carcinomas (HNSCC)
โ Scribed by Leusink, F.K.J.; Roepman, P.; Kummer, J.A.; Koole, R.
- Book ID
- 119336579
- Publisher
- Elsevier Science
- Year
- 2009
- Weight
- 40 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1744-7895
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Background. Prognosis of head and neck squamous cell carcinoma (HNSCC) is strongly associated with cervical lymph node metastasis. Cathepsin-D is a lysosomal protease expressed in all cells. Its role in extracellular matrix degradation is postulated to promote tumor invasion and metastasis. Increase
## Background: The purpose of this study was to evaluate the efficacy of the modern diagnostic evaluation for squamous cell carcinoma metastatic to cervical lymph nodes from an unknown head and neck primary site. ## Methods: One hundred thirty patients were evaluated between june 1983 and june 19
## Abstract ## Objectives/Hypothesis: To discuss our experience with the diagnostic evaluation in patients with squamous cell carcinomas (SCCAs) of the head and neck metastatic to the cervical lymph nodes from an unknown primary site. ## Methods: Between June 1983 and December 2008, 236 patients