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O6-methylguanine-DNA methyltransferase in lymphocytes of the elderly with and without Alzheimers' disease

✍ Scribed by Edwards, J.A.; Wang, L.-G.; Setlow, R.B.; Kaminskas, E.

Book ID
123008281
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
460 KB
Volume
219
Category
Article
ISSN
0921-8734

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## Abstract Promotor hypermethylation is a common event in human cancer. __O^6^‐Methylguanine‐DNA Methyltransferase__ (__MGMT__) is a gene involved in DNA repair, which is methylated in a variety of cancer types. In colorectal cancer and lung cancer, hypermethylation of __MGMT__ has been correlated