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O6-Methylguanine-DNA methyltransferase expression and prognostic value in brain metastases of lung cancers

✍ Scribed by Wu, Pei-Fang; Kuo, Kuan-Ting; Kuo, Lu-Ting; Lin, Yi-Ting; Lee, Wei-Chung; Lu, Yen-Shen; Yang, Chih-Hsin; Wu, Ruey-Meei; Tu, Yong-Kwang; Tasi, Jui-Chang; Tseng, Ham-Min; Tseng, Sheng-Hong; Cheng, Ann-Lii; Lin, Ching-Hung

Book ID
119320256
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
513 KB
Volume
68
Category
Article
ISSN
0169-5002

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## Abstract Promotor hypermethylation is a common event in human cancer. __O^6^‐Methylguanine‐DNA Methyltransferase__ (__MGMT__) is a gene involved in DNA repair, which is methylated in a variety of cancer types. In colorectal cancer and lung cancer, hypermethylation of __MGMT__ has been correlated