The DNA-repair protein O 6 -methylguanine-DNA methyltransferase (alkyltransferase; MGMT) is a major determinant of resistance of cells to various alkylating cytostatic drugs. Its expression in tissues is highly variable, indicating complex regulatory mechanisms involved. Transfection-mediated expres
✦ LIBER ✦
O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells
✍ Scribed by Mirjam Hermisson; Andrea Klumpp; Wolfgang Wick; Jörg Wischhusen; Georg Nagel; Wynand Roos; Bernd Kaina; Michael Weller
- Book ID
- 111179321
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 318 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0022-3042
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Activity of O6-methylguanine-DNA methylt
✍
Jan G. Hengstler; Berno Tanner; Lars Möller; Rolf Meinert; Bernd Kaina
📂
Article
📅
1999
🏛
John Wiley and Sons
🌐
French
⚖ 216 KB
👁 2 views
O6-methylguanine DNA-methyltransferase (
✍
Isabelle Passagne; Alexandre Evrard; Philippe Depeille; Pierre Cuq; Didier Cupis
📂
Article
📅
2006
🏛
Elsevier Science
🌐
English
⚖ 351 KB
O6-methylguanine-DNA methyltransferase g
✍
Christine Rolhion; Frédérique Penault-Llorca; Jean-Louis Kemeny; Fabrice Kwiatko
📂
Article
📅
1999
🏛
John Wiley and Sons
🌐
French
⚖ 169 KB
👁 2 views
Repair of cytotoxic DNA damage by O 6 -methylguanine-DNA methyltransferase (MGMT) is a potentially important factor of chemoresistance to chloroethylnitrosoureas (CE-NUs), commonly used in the treatment of glioblastoma multiforme (GBM). The value of p53 as a prognostic factor in GBMs remains unclear
Chemoresistance to Temozolomide in Human
✍
Qiang Pan; Xue-jun Yang; Hua-min Wang; Xue-tao Dong; Wei Wang; Yu LI; Jing-min L
📂
Article
📅
2011
🏛
Springer-Verlag
🌐
English
⚖ 494 KB
O6-Methylguanine DNA methyltransferase e
✍
Reiko Watanabe; Yoko Nakasu; Hiroshi Tashiro; Koichi Mitsuya; Ichiro Ito; Satosh
📂
Article
📅
2011
🏛
Springer Japan
🌐
English
⚖ 984 KB
Poly(ADP-ribose) polymerase inhibitor AB
✍
Horton, T. M.; Jenkins, G.; Pati, D.; Zhang, L.; Dolan, M. E.; Ribes-Zamora, A.;
📂
Article
📅
2009
🏛
American Association for Cancer Research
🌐
English
⚖ 536 KB