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O3-03-03 In vivo magnetic resonance imaging of amyloid plaques in mice with a non-toxic Aβ derivative

✍ Scribed by Einar M. Sigurdsson; Youssef Z. Wadghiri; Jeffrey A. Blind; Elin Knudsen; Ayodeji Asuni; Marcin Sadowski; Daniel H. Turnbull; Thomas Wisniewski


Book ID
117412761
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
163 KB
Volume
25
Category
Article
ISSN
0197-4580

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## Abstract One of the cardinal pathologic features of Alzheimer's disease (AD) is the formation of senile, or amyloid, plaques. Transgenic mice have been developed that express one or more of the genes responsible for familial AD in humans. Doubly transgenic mice develop “human‐like” plaques, prov