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O3-03-01 Design and chemical synthesis of a magnetic resonance contrast agent for imaging Alzheimer's disease amyloid plaques

✍ Scribed by Joseph F. Poduslo; Geoffry Curran; Jane Peterson; Daniel McCormick; Abdul Fauq; Murad Khan; Thomas Wengenack


Book ID
117412759
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
318 KB
Volume
25
Category
Article
ISSN
0197-4580

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## Abstract One of the cardinal pathologic features of Alzheimer's disease (AD) is the formation of senile, or amyloid, plaques. Transgenic mice have been developed that express one or more of the genes responsible for familial AD in humans. Doubly transgenic mice develop β€œhuman‐like” plaques, prov