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In-Vitro and In-Vivo Study of a Magnetic Resonance Imaging (MRI)/Fluorescent Contrast Agent for Detection in Alzheimer's Disease

✍ Scribed by Robert Ta; Alex X. Li; Mojmir Suchy; Robert H.E. Hudson; Stephen H. Pasternak; Robert Bartha


Book ID
118465786
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
130 KB
Volume
6
Category
Article
ISSN
1552-5260

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## Abstract One of the cardinal pathologic features of Alzheimer's disease (AD) is the formation of senile, or amyloid, plaques. Transgenic mice have been developed that express one or more of the genes responsible for familial AD in humans. Doubly transgenic mice develop β€œhuman‐like” plaques, prov