O-Trimethylsilyl hemithioacetals and ketals. Reaction with organolithiums.
β Scribed by T.H. Chan; B.S. Ong
- Book ID
- 104226034
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- French
- Weight
- 241 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
0-Trimethylsilyl hemithioacetals have been obtained from the Pummerer rel-3 arrangement of a-trimethylsilyl sulfoxides . However, preparation of the hemithioacetal directly from the carbonyl compound was reported only for isolated casesl'4.
π SIMILAR VOLUMES
The importance of the ethylene hemithioacetal or -ketal protecting group in steroid chemistry is well documented.' The oxathiolanes derived from steroids and other aldehydes and
Treatment of dichloromethyl-tris(trimethylsilyl)silane (Me 3 Si) 3 SiΒ±CHCl 2 (1), prepared by the reaction of tris(trimethylsilyl)silane with chloroform in presence of potassium tertbutoxide, with organolithium reagents (molar ratio 1 : 3) affords the bis(trimethylsilyl)methyl-disilanes Me 3 SiSiR 2