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O-demethylation of pyrilamine

โœ Scribed by Fu-Lian Hsu; Shu-Yuan Yeh; Shekhar Munavalli


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
237 KB
Volume
77
Category
Article
ISSN
0022-3549

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Synthesis of pyrilamine-d6
โœ Ian Bird; David E G Shuker ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 224 KB

Pyrilamine-d6(N-[ (4-methoxyphenyl ) methyl 1-N' ,N'di[ H ]methyl-N-2-pyridinyl-l,2-ethanediamine) was synthesised from N-2-[(4-methoxyphenyl)methyl]aminopyridine and 2-(N,N-di[ H3]methylamino)ethyl chloride in 8 3 % yield. The alkyl chloride was prepared in 37% overall yield in a three step reacti