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Nω-Nitro-l-arginine methyl ester protects retinal neurons against N-methyl-d-aspartate-induced neurotoxicity in vivo

✍ Scribed by Chikako Morizane; Kei Adachi; Izumi Furutani; Yasuhiko Fujita; Akinori Akaike; Satoshi Kashii; Yoshihito Honda

Book ID
119414483
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
371 KB
Volume
328
Category
Article
ISSN
0014-2999

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✍ Kazuhide Takada; Yasunari Munemasa; Junko Kuribayashi; Hiromi Fujino; Yasushi Ki 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 686 KB

## Abstract Thalidomide, an inhibitor of tumor necrosis factor‐α (TNF‐α) production, has been indicated to be useful for many inflammatory and oncogenic diseases. In the present study, we examined whether thalidomide (50 mg/kg/day, p.o.) has a protective effect against N‐methyl‐D‐aspartate (NMDA)‐i