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Difluoromethyl ornithine protects against the neurotoxic effects of intrastriatally administered N-methyl-D-aspartate in vivo

✍ Scribed by A. Porcella; D. Fage; C. Voltz; C. Carter; B. Scatton; G. Bartholini


Book ID
115886976
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
345 KB
Volume
199
Category
Article
ISSN
0014-2999

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## Abstract Thalidomide, an inhibitor of tumor necrosis factor‐α (TNF‐α) production, has been indicated to be useful for many inflammatory and oncogenic diseases. In the present study, we examined whether thalidomide (50 mg/kg/day, p.o.) has a protective effect against N‐methyl‐D‐aspartate (NMDA)‐i