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Null alleles of the fourth component of complement andHLAhaplotypes in familial systemic lupus erythematosus

✍ Scribed by John D. Reveille; Frank C. Arnett; Raymond W. Wilson; Wilma B. Bias; Robert H. McLean


Publisher
Springer-Verlag
Year
1985
Tongue
English
Weight
818 KB
Volume
21
Category
Article
ISSN
0093-7711

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πŸ“œ SIMILAR VOLUMES


The in Vivo Metabolism of the Third Comp
✍ Lawrence D. Petz; Runas Powers; James R. Fries; Neil R. Cooper; Halsted R. Holma πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 English βš– 861 KB

## Abstract The in vivo metabolism of purified C3, the third component of complement, labeled with ^125^‐iodine (^125^I‐C3) was studied in 17 normal volunteers and in 24 patients with systemic lupus erythematosus (SLE). The latter had varying degrees of disease severity and differing clinical and s

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## Abstract We observed two sisters with lupus‐like syndrome with homozygous C3 deficiencies. A 19‐year‐old woman and her 15‐year‐old sister developed malar rash, arthralgia, and photosensitivity, but antinuclear antibodies and LE cell preparations were negative. The older sister experienced recurr

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## Abstract The occurrence of systemic lupus erythematosus (SLE) is reported in 2 pairs of male siblings. Since the occurrence of idopathic SLE is uncommon in the male, these cases provide additional support to the hypothesis that genetic factors play an important role in pathogenesis. Of additiona