Null alleles of the fourth component of complement andHLAhaplotypes in familial systemic lupus erythematosus
β Scribed by John D. Reveille; Frank C. Arnett; Raymond W. Wilson; Wilma B. Bias; Robert H. McLean
- Publisher
- Springer-Verlag
- Year
- 1985
- Tongue
- English
- Weight
- 818 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0093-7711
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The in vivo metabolism of purified C3, the third component of complement, labeled with ^125^βiodine (^125^IβC3) was studied in 17 normal volunteers and in 24 patients with systemic lupus erythematosus (SLE). The latter had varying degrees of disease severity and differing clinical and s
## Abstract We observed two sisters with lupusβlike syndrome with homozygous C3 deficiencies. A 19βyearβold woman and her 15βyearβold sister developed malar rash, arthralgia, and photosensitivity, but antinuclear antibodies and LE cell preparations were negative. The older sister experienced recurr
## Abstract The occurrence of systemic lupus erythematosus (SLE) is reported in 2 pairs of male siblings. Since the occurrence of idopathic SLE is uncommon in the male, these cases provide additional support to the hypothesis that genetic factors play an important role in pathogenesis. Of additiona