Dedicated to Prof. Dr. Wilhelm Fleischhacker on the occasion of his 60th birthday (8.X1.91) ~ ~~ The chemical syntheses of the phosphorothioate of (2'-5')adenylate dimer (see 6a, 6b) and trimer (see 1 la, 1 lb, 12a, 12b) as well as of their 5'-monophosphates (see 15a, 15b, 16a, 16b) using the phosp
Nucleotides. Part XXVIII. Chemical syntheses of the 2′-5′-cordycepin-trimer core
✍ Scribed by Ramamurthy Charubala; Eugen Uhlmann; Frank Himmelsbach; Wolfgang Pfleiderer
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- German
- Weight
- 844 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Part XXVII [I].
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The 5'-amino-5'-deoxy-2',3'-0-isopropylideneadenosine (4) was obtained in pure form from 2',3'-0-isopropylideneadenosine (l), without isolation of intermediates 2 and 3. The 2-(4-nitrophenyl)ethoxycarbonyl group was used for protection of the NH2 functions of 4 ( 4 7 ) . The selective introduction o