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Nucleotide sequence of the triose phosphate isomerase gene of Escherichia coli

✍ Scribed by Pichersky, E. ;Gottlieb, L. D. ;Hess, J. F.


Publisher
Springer
Year
1984
Tongue
English
Weight
707 KB
Volume
195
Category
Article
ISSN
0026-8925

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✦ Synopsis


We report here the complete nucleotide sequence of the E. coli triose phosphate isomerase gene. The gene encodes a polypeptide of 255 amino acids which is approximately 46% homologous to eukaryotic triose phosphate isomerases, and approximately 38% homologous to the enzyme from a thermophilic bacterium, Bacillus stearothermophilus. The nucleotide sequence is 55% homologous to that of the corresponding gene in the yeast Saccharomyces cerevisiae. To our knowledge, this is the first report of the sequence of a gene coding a glycolytic enzyme from a prokaryotic organism.


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