Nucleotide competing reverse transcriptase inhibitors: Discovery of a series of non-basic benzofurano[3,2-d]pyrimidin-2-one derived inhibitors
✍ Scribed by James, Clint A.; DeRoy, Patrick; Duplessis, Martin; Edwards, Paul J.; Halmos, Teddy; Minville, Joannie; Morency, Louis; Morin, Sébastien; Simoneau, Bruno; Tremblay, Martin; Bethell, Richard; Cordingley, Michael; Duan, Jianmin; Lamorte, Louie; Pelletier, Alex; Rajotte, Daniel; Salois, Patrick; Tremblay, Sonia; Sturino, Claudio F.
- Book ID
- 121405026
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 523 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0960-894X
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5-Alkyl-2-[(methylthiomethyl)thio]-6-(benzyl)-pyrimidin-4-(1H)-ones as Potent Non-Nucleoside Reverse Transcriptase Inhibitors of S-DABO Series. -Novel pyrimidinone derivatives (VII) (S-DABO) are synthesized and tested for their reverse transcriptase inhibitory activity as well as their anti-HIV act