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Nucleosome Stacking Defines The Structural And Mechanical Properites Of Chromatin Fibers

✍ Scribed by Chien, Fan-Tso; Kruithof, Maarten; Routh, Andrew; Rhodes, Daniela; van Noort, John


Book ID
119204589
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
155 KB
Volume
96
Category
Article
ISSN
0006-3495

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An atomic force microscope was used to image and stretch single synthetic chromatin fibers consisting of twelve core nucleosomes with no linker histones. Peaks in the forcecurves are attributed to sequential detachment of nucleosomes from the glass support. The short distances between peaks and reve