In a recent report ', the structure originally advanced for the nucleoside antibiotic, gougerotin, (I) 3 was revised to structure II on the basis of chemical and physical evidence. The establishment of the carbohydrate moiety as a 4-aminohexose derivative and the positional assignment of the peptid
โฆ LIBER โฆ
Nucleosides, XXV. On the structure of aspiculamycin: Its identity with the nucleoside antibiotic gougerotin
โ Scribed by Frieder W. Lichtenthaler; Tetsuo Morino; Heinrich M. Menzel
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- French
- Weight
- 249 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0040-4039
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Abstmctz 2',3'-Di-0-mesyl-S'-O-trityl-lyxo-uridine 1 tracted with secondary amines to produce cnaminooucleosidcs t-d and 3a-d. Intermediacy of 2'-ketouridine was essential for the anomerisation and enamiue formation to take place. The structure of the gcnamine was established unambiguously by anal y