Nucleophilic substitutions on 2-Chloro-3-Nitroquinoxaline
โ Scribed by R. Nasielski-Hinkens; M. Kaisin; D. Grandjean; M. Loos; J. Nasielski
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 476 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0037-9646
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Reactions of 4โchloroโ3โnitrocoumarin with a variety of nucleophiles produced a number of novel substituted coumarins. Hard and borderline nucleophiles exclusively substitute chlorine in position **4**, while soft nucleophiles substitute the nitro group in position 3 (except for iodide)
## Abstract magnified image In some nucleophilic substitution reactions of 2โcyanoโ3โnitroimidazo[1,2โ__a__]pyridine, nitrogen (alkylamines, guanidine) and oxygen nucleophiles (alkoxides) underwent substitution of the 2โcyano group, while sulfur nucleophiles (alkylthiols) underwent substitution of
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The kinetics of the reactions of 2-chloro-3-nitropyridine (ortho-like) and 5-nitro ( para-like) isomer with morpholine and piperidine were studied in methanol and benzene at several amine concentrations and temperatures in the range 25 -45ยฐC. The data show that k 3-NO 2 /k 5-NO 2 ratios are less tha