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Some nucleophilic substitutions in 2-cyano-3-nitroimidazo[1,2-a]pyridine

✍ Scribed by Lucina Arias; Héactor Salgado-Zamora; Elena Campos; Alicia Reyes; Humberto Cervantes; Edward C. Taylor

Publisher: Journal of Heterocyclic Chemistry
Year: 2006
Tongue: English
Weight: 296 KB
Volume: 43
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570430307

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✦ Synopsis

Abstract

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In some nucleophilic substitution reactions of 2‐cyano‐3‐nitroimidazo[1,2‐a]pyridine, nitrogen (alkylamines, guanidine) and oxygen nucleophiles (alkoxides) underwent substitution of the 2‐cyano group, while sulfur nucleophiles (alkylthiols) underwent substitution of the 3‐nitro group.

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