A fluorine-18 labeled analogue of D-talose, 2-deoxy-2-[18F]fluoro-D-talose ([18F]FDT), was synthesized via nucleophilic fluorination with [18F]fluoride ion and its biodistributions in animals were examined. Radiofluorination of benzyl 3,5,6-tri-O-benzyl-2-O-(trifluoromethanesulfonyl)-alpha-D-galac t
✦ LIBER ✦
Nucleophilic radiosynthesis of 2-[18F]fluoro-2-deoxy-d-galactose from Talose triflate and biodistribution in a porcine model
✍ Scribed by Kim Frisch; Dirk Bender; Søren B. Hansen; Susanne Keiding; Michael Sørensen
- Book ID
- 116799695
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 733 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0969-8051
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## Abstract We have synthesized __β__‐O‐D‐galactopyranosyl‐(1,4′)‐2′‐[^18^F]fluoro‐2′‐deoxy‐D‐glucopyranose (2′‐[^18^F]fluorodeoxylactose, ^18^FDL) using an enzymatic method starting from ^18^FDG in order to evaluate this compound with regard to its usefulness for __in vivo__ visualization of the e
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