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Nucleophilic Attack at Sulfoxide: The Methanethiol-Mediated Cleavage of a Thiane 1-Oxide

✍ Scribed by Schostarez, Heinrich J.; Schwartz, Theresa M.


Book ID
125995381
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
210 KB
Volume
61
Category
Article
ISSN
0022-3263

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## Abstract A new series of 2,3‐disubstituted quinazolin‐4(3__H__)‐one derivatives was synthesized by nucleophilic attack at C(2) of the corresponding key starting material 2‐propyl‐4__H__‐3,1‐benzoxazin‐4‐one (__Scheme 2__). The reaction proceeded __via__ amidinium salt formation (__Scheme 3__) ra