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Nucleophilic additions to (4S)-1-alkylidene-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones

✍ Scribed by Marı́a Luisa Heredia; Elena de la Cuesta; Carmen Avendaño


Book ID
108371108
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
156 KB
Volume
57
Category
Article
ISSN
0040-4020

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✍ María Fernandez; María L. Heredia; Elena de la Cuesta; Carmen Avendaño 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 351 KB

The enamine character of the CH2-C(lla)=N(ll) fragment in the title compounds was studied. Congxatmds I gave l-dimethylaminomethylene products $ after Vilsmeier reaction. The l-formyl derivatives, obtained by alkaline hydrolysis of 5, were isolated as enol tautome~s and were vea'y unstable in acid m