Nucleophilic Addition of Nitrones to Ket
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Anders BΓΈgevig; Kurt V. Gothelf; Karl Anker JΓΈrgensen
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Article
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2002
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John Wiley and Sons
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English
β 210 KB
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A new organic reaction has been discovered in which nitrones react with carbonyl compounds in an aldoltype reaction to give functionalized beta-hydroxynitrones. The alpha-carbon atom of the nitrone undergoes a nucleophilic addition reaction to electron-deficient ketones, such as alpha-ketoesters, al