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Nucleobase- and p-Glycoprotein-Mediated Transport of AG337 in a Caco-2 Cell Culture Model

✍ Scribed by Hu, Ming; Chen, Jiyue

Book ID
127221738
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
99 KB
Volume
1
Category
Article
ISSN
1543-8384

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P-glycoprotein–mediated transport of ber
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✍ Han-Joo Maeng; Ho-Jung Yoo; In-Wha Kim; Im-Sook Song; Suk-Jae Chung; Chang-Koo S πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 116 KB

The objective of this study was to investigate the mechanisms by which berberine is transported in the secretory and absorptive directions across Caco-2 cell monolayers. The basolateral-to-apical (B-A) flux was 30-fold greater than the apical-to-basolateral flux and temperature dependent (i.e., dras