Nucleic acid–metal interactions: V. The effect of silver(I) on the structures of A- and B-DNA forms
✍ Scribed by Bengt Nordén; Yukio Matsuoka; Tomas Kurucsev
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1986
- Tongue
- English
- Weight
- 740 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0006-3525
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The melting temperature of a natural DNA is decreased in the presence of increasing amounts of copper ions, whereas other divalent metal ions stabilize the DNA secondary structure a t low ionic strength. At 1.28 X lO-4M, Cuz+ produces a decrease of T,,, depending on base composition. At very low Cu\
and the Rnlfiriiore City Hospitals, Baltiiizore, ~Ua~ylancl 2li?24 ## Synopsis Potentiometric titration curves of the silver(1) complexes of cytidine, adenosine, and irridine show little liptake of base below pH 7, unlike the cllrve for silver(It-giianositie, which shows extensive base uptake at