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Nuclear/cytoplasmic localization of Akt activity in the cell cycle

✍ Scribed by M. Rosner; M. Hanneder; A. Freilinger; M. Hengstschläger

Publisher
Springer
Year
2007
Tongue
English
Weight
161 KB
Volume
32
Category
Article
ISSN
0939-4451

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## Abstract BRD7, a novel bromodomain gene, is identified to be associated with nasopharyngeal carcinoma (NPC). Decreased or loss of expression of BRD7 was detected in NPC biopsies and cell lines. Overexpression of BRD7 could inhibit NPC cell growth and arrest cells in cell cycle by transcriptional