Nuclear S100A4 is a novel prognostic marker in colorectal cancer
✍ Scribed by Kjetil Boye; Jahn M. Nesland; Berit Sandstad; Gunhild M. Mælandsmo; Kjersti Flatmark
- Book ID
- 116430478
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 202 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0959-8049
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Background and Objectives: Expression of S100A4, a small calcium-binding protein, in breast, oesophagus and gall bladder cancers is shown to be associated with adverse clinical outcome. We retrospectively examined the correlation of S100A4 expression and outcome in patients with colorectal cancer. M
## Abstract Chromosomal region 18q21 is frequently deleted in colorectal cancer (CRC) and is associated with poor prognosis. Potential tumor suppressor mechanisms altered by 18q21 deletion include mediation of TGFβ signaling by SMADs. Following the definition of __SMAD4__ deletion as a negative pre