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Nuclear RNA Synthesis in Human Leukaemic Cells

✍ Scribed by TRYFIATES, GEORGE P.; LASZLO, JOHN


Book ID
109654757
Publisher
Nature Publishing Group
Year
1967
Tongue
English
Weight
352 KB
Volume
213
Category
Article
ISSN
0028-0836

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Several observations have been made about the associations of small nuclear RNAs (snRNAs) in human cells. When nuclear RNA was extracted with phenol and chloroform under standard nondenaturing conditions, the proportion of the nuclear snRNA content that cosedimented with high molecular weight RNA wa

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We have examined some aspects of the biosynthesis of human small nuclear RNAs (snRNAs). The sensitivity of U5 and U4 snRNA synthesis to a-amanitin in whole cells suggests that RNA polymerase I I is involved in the synthesis of these RNA species, in addition to that of U1, U2, and U3 snRNA. Two RNA b