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Nuclear receptors, bile acids and cholesterol homeostasis series – Bile acids and pregnancy

✍ Scribed by Abu-Hayyeh, Shadi; Papacleovoulou, Georgia; Williamson, Catherine


Book ID
120265139
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
417 KB
Volume
368
Category
Article
ISSN
0303-7207

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✍ Saul J. Karpen 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 52 KB

Bile acids are essential for the solubilization and transport of dietary lipids and are the major products of cholesterol metabolism. Results presented here show that bile acids are physiological ligands for the farnesoid X receptor (FXR), an orphan nuclear receptor. When bound to bile acids, FXR re