## Abstract MRI is becoming an increasingly important tool to assess iron overload disorders, but the complex nature of protonโiron interactions has troubled noninvasive iron quantification. Intersite and intersequence variability as well as methodological inaccuracies have been limiting factors to
Nuclear magnetic resonance parameters for monitoring coagulation of liver tissue
โ Scribed by Dina Carasso; Uzi Eliav; Gil Navon
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 123 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0740-3194
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โฆ Synopsis
Abstract
A new NMR parameter is suggested as a sensitive tool for monitoring thermal coagulation of liver tissue. That parameter is the proton magnetization exchange time (ฯ~MEX~) between water and the proteins. ฯ~MEX~ was very sensitive to coagulation and insensitive to temperature, therefore representing only damage to the tissue, independent of effects caused by temperature fluctuations. The measurement of ฯ~MEX~ by two different methods revealed the existence of two or more groups of proteins, characterized by their different transverse relaxation time, and ฯ~MEX~. Magn Reson Med, 2005. ยฉ 2005 WileyโLiss, Inc.
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