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Nuclear localization of long-VEGF is associated with hypoxia and tumor angiogenesis

โœ Scribed by Yifat Rosenbaum-Dekel; Alisa Fuchs; Evgeny Yakirevich; Aviva Azriel; Salam Mazareb; Murray B. Resnick; Ben-Zion Levi


Book ID
116290554
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
696 KB
Volume
332
Category
Article
ISSN
0006-291X

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The pituitary tumor transforming gene 1 (PTTG1) protein is cell-cycle regulated and is identified as a human securin that inhibits sister chromatid separation and is involved in transformation and tumorigenesis. PTTG1 has very low or undetectable expression in most normal human tissues, but it is ab