𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Nuclear in vitro method of continuously evaluating release rates of solid dosage forms

✍ Scribed by William J. McClintock; Dane O. Kildsig; Wayne V. Kessler; Gilbert S. Banker


Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
333 KB
Volume
57
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Once-a-day controlled-release dosage for
✍ Yihong Qiu; J. Garren; E. Samara; G. Cao; C. Abraham; H.S. Cheskin; K.R. Engh πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 207 KB πŸ‘ 1 views

During formulation design of a once-daily controlled release matrix system of divalproex sodium, the in vitro dissolution test (USP II, 100 rpm, pH 6.8 buffer) was found to result in release rates that were slower than in vivo absorption. The test method also did not sufficiently discriminate formul

Pharmacokinetic evaluation of novel sust
✍ Meir Bialer; Michael Friedman; Joseph Dubrovsky; Itamar Raz; Oded Abramsky πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 444 KB πŸ‘ 2 views

1. Five new sustained-release dosage forms of valproic acid (VPA) were developed. 2. The new sustained-release formulations were administered to six healthy subjects for comparison with a standard tablet and an i.v. preparation of the drug. 3. Three of the formulations exhibited a more prolonged and

Gastrointestinal bioavailability: Determ
✍ William R. Gillespie; Peter Veng-Pedersen πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 188 KB πŸ‘ 2 views

If a linear relationship exists between the rate of drug release or dissolution in the gastrointestinal tract, f ( t ) , and the resulting systemic drug level, c(t), that relationship can be expressed as a convolution: where c&) is the systemic drug concentration resulting from the instantaneous in