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NS398 induces apoptosis in non-small cell lung cancer cells

✍ Scribed by Rong Qiu; Jian Chen; Jun Sima; Xiangdi Shen; Dandan Liu; Jian Shen

Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 266 KB
Volume: 138
Category: Article
ISSN: 1432-1335
DOI: 10.1007/s00432-011-1080-3

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## Abstract p53‐dependent apoptosis is important for the efficacy of cancer treatment, and tumors carrying mutant p53 are often resistant to chemotherapy. Non‐small cell lung cancer (NSCLC) cells generally exhibit resistance to apoptosis following treatment with many cytotoxic drugs. The new molecu