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Nrf2 is involved in inhibiting Tat-induced HIV-1 long terminal repeat transactivation

โœ Scribed by Hong-Sheng Zhang; Hong-Yan Li; Yue Zhou; Meng-Ran Wu; Hong-Sen Zhou


Book ID
113630878
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
915 KB
Volume
47
Category
Article
ISSN
0891-5849

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Chromatin remodeling, especially in relation to the transactivator Tat, is an essential event for human immunodeficiency virus-1 (HIV-1) transcription. Curcumin has been shown to suppress pathways linked to HIV-1 replication. We investigated whether curcumin had the potential to inhibit Tat-induced