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Novel α-arylnitriles synthesis via Ni-catalyzed cross-coupling of α-bromonitriles with arylboronic acids under mild conditions

✍ Scribed by Yang, Yingying; Tang, Shan; Liu, Chao; Zhang, Huimin; Sun, Zhexun; Lei, Aiwen


Book ID
120445055
Publisher
Royal Society of Chemistry
Year
2011
Tongue
English
Weight
397 KB
Volume
9
Category
Article
ISSN
1477-0520

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## Abstract A simple and efficient copper‐salt catalyzed __N__‐arylation of nucleobases is reported. In a mixed solvent of MeOH and H~2~O, the coupling products were obtained in moderate to excellent yields at room temperature within a short time. A variety of substituted __N__‐aryl nucleobases can