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Novel α-Amino-3-hydroxy-5-methylisoxazole-4-propionate Receptor Antagonists: Synthesis and Structure−Activity Relationships of 6-(1 H -Imidazol-1-yl)- 7-nitro-2,3(1 H ,4 H )-pyrido[2,3- b ]pyrazinedione and Related Compounds

✍ Scribed by Ohmori, Junya; Kubota, Hirokazu; Shimizu-Sasamata, Masao; Okada, Masamichi; Sakamoto, Shuichi


Book ID
120830872
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
408 KB
Volume
39
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Novel AMPA Receptor
✍ J. OHMORI; M. SHIMIZU-SASAMATA; M. OKADA; S. SAKAMOTO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

Novel AMPA Receptor Antagonists: Synthesis and Structure-Activity Relationships of 1-Hydroxy-7-(1H-imidazol-1-yl)-6-nitro-2,3(1H,4H) quinoxalinedione and Related Compounds. -A series of title compounds, e.g. (VII), is prepared and evaluated for their affinity towards AMPA receptors. Derivative (VII